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Zoledronic acid, also known as zoledronate and sold under the brand name Zometa among others, [7] by Novartis among others, is a medication used to treat a number of bone diseases. [3] These include osteoporosis , high blood calcium due to cancer , bone breakdown due to cancer, Paget's disease of bone [ 3 ] and Duchenne muscular dystrophy (DMD).
3 (phosphonate) groups covalently linked to carbon determine both the name "bisphosphonate" and the function of the drugs. Bis refers to the fact that there are two such groups in the molecule. The long side-chain (R 2 in the diagram) determines the chemical properties, the mode of action and the strength of bisphosphonate drugs.
[3] Further development has not resulted in the placing on the market of compounds in equal potency. Arylalkyl substitutes of pamidronate are among the most recent bisphosphonates to be used clinically where the hydroxyl group in position R 2 has been omitted to ensure stability.
Q3: The third quarter is during the months of July, August and September. As companies report every quarter, if you receive a statement from July 1 to Sept. 30, this would indicate how the company ...
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Etidronic acid is a bisphosphonate used to strengthen bone, treat osteoporosis, and treat Paget's disease of bone.. Bisphosphonates primarily reduce osteoclastic activity, which prevents bone resorption, and thus moves the bone resorption/formation equilibrium toward the formation side and hence makes bone stronger on the long run.
Why Everyone REALLY Needs to Change Their Toothbrush Every 3 Months. Luisa Colón. December 2, 2023 at 8:00 AM. What Happens When You Don't Change Your Toothbrush Westend61 - Getty Images.
The stated goal of this program is the capability of producing 150,000,000 doses of pandemic vaccine within six months of declaring a flu pandemic. [ 164 ] In April 2014, Novartis divested its consumer health section with $3.5 billion worth of assets into a new joint venture with GlaxoSmithKline , named GSK Consumer Healthcare, of which ...
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