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Keratoconus (KC) is a disorder of the eye that results in progressive thinning of the cornea. [3] This may result in blurry vision, double vision, nearsightedness, irregular astigmatism, [4] and light sensitivity leading to poor quality-of-life.
Corneal cross-linking (CXL) with riboflavin (vitamin B 2) and UV-A light is a surgical treatment for corneal ectasia such as keratoconus, PMD, and post-LASIK ectasia. It is used in an attempt to make the cornea stronger. According to a 2015 Cochrane review, there is insufficient evidence to determine if it is useful in keratoconus. [2]
Corneal pachymetry may be useful in confirming the diagnosis. Treatment usually consists of vision correction with eyeglasses or contact lenses. Intacs implants, corneal collagen cross-linking, and corneal transplant surgery are additional options. Surgery is reserved for individuals who do not tolerate contact lenses.
Keratoconus, a progressive, noninflammatory, bilateral, asymmetric disease, characterized by paraxial stromal thinning and weakening that leads to corneal surface distortion. [ 2 ] Keratoglobus , a rare noninflammatory corneal thinning disorder, characterised by generalised thinning and globular protrusion of the cornea.
There is a loss of contrast sensitivity, so that contours, shadows, and color vision are less vivid. The loss in contrast sensitivity can be quickly and easily measured by a contrast sensitivity test like Pelli Robson performed either at home or by an eye specialist. [citation needed]
Keratoconus in itself is a pattern of the entire cornea, therefore every measurement just focusing on one layer, might not be enough for a state of the art diagnosis. Especially early cases of keratoconus might be missed by a plain topographic measurement, which is critical if refractive surgery is being considered. [7]
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Lifitegrast was approved by the US FDA for the treatment of the condition in 2016. [52] Varenicline (Tyrvaya by Oyster Point Pharma) was approved by the US FDA for the treatment of dry eye disease in October 2021. [53] [54] Oral n-acetylcysteine (NAC), [55] hyaluronic acid and/or rebamipide-based eye drops [56] [57] may also be effective for ...