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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
You may have also heard of ketamine therapy, which uses ketamine, a drug that was originally used as an animal anesthetic, administered in a clinical setting to improve mental health symptoms.
Ketamine therapy primarily treats depression, PTSD, anxiety, suicidality, and other mental health conditions. Most patients return for two follow-up ketamine treatments we refer to as boosters on ...
MDMA-assisted psychotherapy is also currently in Phase 2 trials for eating disorders, [11] anxiety associated with life-threatening illness, [12] and social anxiety in autistic adults. [ 13 ] Psilocybin , a compound in psilocybin mushrooms that serves as a prodrug for psilocin , is currently being investigated in clinical trials of Hallucinogen ...
In 2019, the US Food and Drug Administration approved a nasal spray that uses esketamine, a cousin of ketamine, for treatment-resistant depression. The researchers on the new study say that ...
Ketamine potentiates the sedative effects of propofol [85] and midazolam. [86] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [87] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
Five subjects dropped out of the ketamine study; of these, four were taking valproate and one was being treated with lithium. One patient showed signs of hypomania following ketamine administration and two experienced low mood. This study demonstrates a rapid-onset antidepressant effect of ketamine in a small group of patients with bipolar ...
Some off label antidepressants are low dose ketamine and highly serotonergic catecholamines (including very controlled use of MDMA in the treatment of PTSD and crippling depression/anxiety). [ citation needed ] For lethargic syndromes, dysthymia , or caffeine-resistant amotivation, a dopaminergic stimulant such as methylphenidate , or even ...