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Monotherapy with a β3 adrenergic agonist may be preferred in older patients, those with high anticholinergic burden, and older adults with multiple comorbidities. [11] An ambulatory blood pressure monitoring study showed that treatment with vibegron was not associated with clinically meaningful effects on blood pressure or heart rate.
Trospium chloride is used for the treatment of overactive bladder with symptoms of urge incontinence and frequent urination. [3] [4] [2]It should not be used with people who retain urine, who have severe digestive conditions, myasthenia gravis, narrow-angle glaucoma, or tachyarrhythmia.
Combined use of medications with anticholinergics may cause synergistic (supra-additive), additive, or antagonistic interactions, leading to no therapeutic effect or overdosing. [25] [26] Below listed are some medications or food that can interact with anticholinergics. Medications indicated for: Irregular heartbeat, e.g. disopyramide ...
[medical citation needed] It is characterized by uninhibited bladder contractions causing an uncontrollable urge to void. [medical citation needed] Urinary frequency, urge incontinence and nocturnal incontinence occur. [medical citation needed] Abnormal bladder contractions that coincide with the urge to void can be measured by urodynamic studies.
Overactive bladder is characterized by a group of four symptoms: urgency, urinary frequency, nocturia, and urge incontinence. Urge incontinence is not present in the "dry" classification. [12] Urgency is considered the hallmark symptom of OAB, but there are no clear criteria for what constitutes urgency and studies often use other criteria. [1]
Medications are not recommended for those with stress incontinence and are only recommended in those with urge incontinence who do not improve with bladder training. [44] While medications have been shown to be helpful with treating urinary incontinence, studies have shown that the first line treatment that's most effective against urinary ...
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