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This gave rise to the de novo protein synthesis theory: the formation of a long-term memory requires the synthesis of new proteins. Eric Kandel established many of the biochemical markers of learning and memory in the Aplysia (California sea slug) in the 1970s, as his findings suggested potential pathways surrounding protein synthesis. [2]
Their correlation maps highlighted the same areas already identified by the other researchers. [21] This was important because it demonstrated a convergence of methods all leading to the same areas being involved in the DMN. Since then other networks have been identified, such as visual, auditory, and attention networks.
The major difference between diffusion maps and principal component analysis is that only local features of the data are considered in diffusion maps as opposed to taking correlations of the entire data set. defines a random walk on the data set which means that the kernel captures some local geometry of data set. The Markov chain defines fast ...
Lobes in this cortex are more closely associated with memory and in particular autobiographical memory. [15] The temporal lobes are also concerned with recognition memory. This is the capacity to identify an item as one that was recently encountered. [16] Recognition memory is widely viewed as consisting of two components, a familiarity ...
Common signs of dyschronometria are often generic to cerebellar ataxia, including a lack of spatial awareness, poor short term memory, and inability to keep track of time. [citation needed] [5] The defining symptoms, while not completely understood, involve time perception. For example, when asked to wait for thirty seconds, or tap every second ...
Two molecular mechanisms for synaptic plasticity involve the NMDA and AMPA glutamate receptors. Opening of NMDA channels (which relates to the level of cellular depolarization) leads to a rise in post-synaptic Ca 2+ concentration and this has been linked to long-term potentiation, LTP (as well as to protein kinase activation); strong depolarization of the post-synaptic cell completely ...
This distance is robust to noise, since the distance between two points depends on all possible paths of length between the points. From a machine learning point of view, the distance takes into account all evidences linking x i {\displaystyle x_{i}} to x j {\displaystyle x_{j}} , allowing us to conclude that this distance is appropriate for ...
Memory implantation techniques were developed in the 1990s as a way of providing evidence of how easy it is to distort people's memories of past events. Most of the studies on memory implantation were published in the context of the debate about repressed memories and the possible danger of digging for lost memories in therapy. The successful ...