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Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa.
The most serious and common adverse side effects associated with anticoagulants are increased risk of bleeding, both nonmajor and major bleeding events. [37] The bleeding risk depends on the class of anticoagulant agent used, the patient's age, and pre-existing health conditions.
Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]
Additionally, many medications – both prescribed and over-the-counter - have common side effects, such as lightheadedness or confusion, that can lead to falls, so it is important for people to ...
The UK medicines regulator MHRA warned that fluoroquinolones were linked to rare but occasionally severe and irreversible side effects, including tendon rupture, muscle and joint pain and nerve ...
Common side effects include bleeding. [8] Other serious side effects may include spinal hematoma and anaphylaxis. [8] It is unclear if use in pregnancy and breastfeeding is safe. [1] Compared to warfarin it has fewer interactions with other medications. [9] It works by blocking the activity of the clotting protein factor Xa. [8]
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Most patients can tolerate anticoagulation for years (and even decades) without serious side effects. However, there are certain subsets of individuals who are unable to tolerate anticoagulation, and may be subject to increased bleeding or hematological risks. These patients may be good candidates for LAAO: [5]
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