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  2. Transferrin saturation - Wikipedia

    en.wikipedia.org/wiki/Transferrin_saturation

    Transferrin saturation (TS), measured as a percentage, is a medical laboratory value. It is the value of serum iron divided by the total iron-binding capacity [1] of the available transferrin, the main protein that binds iron in the blood, this value tells a clinician how much serum iron is bound.

  3. Total iron-binding capacity - Wikipedia

    en.wikipedia.org/wiki/Total_iron-binding_capacity

    Transferrin (mg/dL) = 0.8 x TIBC (μg of iron/dL) – 43; Transferrin (mg/dL) = 0.7 x TIBC (μg of iron/dL) To measure TIBC in the blood is less expensive than a direct measurement of transferrin. [4] [5] The TIBC should not be confused with the unsaturated iron-binding capacity or UIBC (LOINC 2501-5, 22753-8 & 35216-1). The UIBC is calculated ...

  4. Serum iron - Wikipedia

    en.wikipedia.org/wiki/Serum_iron

    Serum iron is a medical laboratory test that measures the amount of circulating iron that is bound to transferrin and freely circulate in the blood. Clinicians order this laboratory test when they are concerned about iron deficiency, which can cause anemia and other problems. 65% of the iron in the body is bound up in hemoglobin molecules in red blood cells.

  5. Iron tests - Wikipedia

    en.wikipedia.org/wiki/Iron_tests

    Iron tests are groups of clinical chemistry laboratory blood tests that are used to evaluate body iron stores or the iron level in blood serum. Other terms used for the same tests are iron panel , iron profile , iron indices , iron status or iron studies .

  6. Sideroblastic anemia - Wikipedia

    en.wikipedia.org/wiki/Sideroblastic_anemia

    Serum Iron: high; increased ferritin levels; decreased total iron-binding capacity; high transferrin saturation; Hematocrit of about 20-30%; The mean corpuscular volume or MCV is usually normal or low for congenital causes of sideroblastic anemia but normal or high for acquired forms.

  7. Transferrin - Wikipedia

    en.wikipedia.org/wiki/Transferrin

    When plasma transferrin levels rise, there is a reciprocal decrease in percent transferrin iron saturation, and a corresponding increase in total iron binding capacity in iron deficient states [22] A decreased plasma transferrin level can occur in iron overload diseases and protein malnutrition.

  8. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    Once the serum ferritin and transferrin saturation are within the normal range, maintenance phlebotomies may be needed in some (depending upon the rate of reabsorption of iron), scheduled at varying frequencies to keep iron stores within normal range. [39] A phlebotomy session typically draws between 450 and 500 mL of blood. [42]

  9. Hemochromatosis type 4 - Wikipedia

    en.wikipedia.org/wiki/Hemochromatosis_type_4

    Diagnosis is based upon identification of symptoms, medical history, family history, and laboratory tests. Blood tests may show high levels of ferritin and low, normal, or high levels of transferrin saturation, depending on the form of hemochromatosis. The diagnosis must be confirmed by genetic testing for SLC40A1 mutations. [14]

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