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Equine EPM is caused by the parasites that exhibit SAG1, SAG5, and SAG6. SAG1 and SAG5 are responsible for the majority of EPM cases in horses. Horses produce antibodies to these surface antigens. Serum antibody testing is available that measures levels of these antibodies in the blood of horses, which is helpful in diagnosing EPM in an ataxic ...
Ponazuril (), sold by Merial, Inc., [1] now part of Boehringer Ingelheim, [2] under the trade name Marquis (15% w/w ponazuril), is a drug currently approved for the treatment of equine protozoal myeloencephalitis (EPM) in horses, caused by coccidia Sarcocystis neurona.
Neospora hughesi is an obligate protozoan apicomplexan parasite that causes myelitis and equine protozoal myeloencephalitis (EPM) in horses, and has only been documented in North America. [1] EPM is a neurological disease from lesions in the spinal cord , brain stem , or brain from parasites such as N. hughesi or Sarcocystis neurona . [ 2 ]
The protozoan, S. neurona, is a member of the genus Sarcocystis, and is most commonly associated with equine protozoal myeloencephalitis (EPM). [2] S. neurona can be easily cultivated and genetically manipulated, hence its common use as a model to study numerous aspects of cell biology .
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The feet should be cleaned every time the horse is ridden, and if the horse is not ridden, it is still best practice to check and clean feet frequently. Daily cleaning is recommended in many management books, though if horses are on turnout and not being ridden, a weekly hoof check of healthy horses is often sufficient during good weather.
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The same should be done when cooling down. Ensure that the horse is cared for, for an issues to the immune system and allowed to recover before continuing training. [1] A horse ideally should receive exercise once, or possibly twice a day, every day, to prevent the recurrence of ER. If possible, avoid breaks in the horse's exercise schedule. [1]
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