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Research into genetic factors and potential treatments is still underway, but Scherer said the current best approach to medical treatment of obesity is GLP-1 medications.
Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity. [4] [5]
According to Patrick Corrigan, the editor of the journal Stigma and Health, even the most well-intentioned efforts to reduce stigma break down in the face of reality. In one study, researchers told 10- to 12-year-olds all the genetic and medical factors that contribute to obesity. Afterward, the kids could recite back the message they received ...
Obesity is a monthly peer-reviewed medical journal covering research into obesity. It was established in 1993 under the name Obesity Research , obtaining its current name in 2006. [ 1 ] [ 2 ] It is published by Wiley-Blackwell on behalf of the Obesity Society , of which it is the official journal.
Numerous studies aimed to provide insight into genetic, economic, and/or environmental causes of obesity. According to the "thrifty gene hypothesis, [18] a genetic theory explaining rising obesity rates, certain individuals are genetically predisposed to metabolize food more efficiently than others as a result of human evolution. In times of ...
Prentice et al. [17] predicted that the emerging molecular genetics field would ultimately provide a way to test between the adaptive 'thrifty gene' idea and the non-adaptive 'drifty gene' idea because it would be possible to find signatures of positive selection in the human genome, at genes that are linked to both obesity and type 2 diabetes ...
Fat mass and obesity-associated protein, also known as alpha-ketoglutarate-dependent dioxygenase FTO, is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first messenger RNA (mRNA) demethylase that has been identified. [ 5 ]
A 2010 study published in the American Journal of Clinical Nutrition closely tracked 373,803 people over a period of 8 years across 10 countries. At its conclusion, the study reported that meat consumption ( processed meat , red meat , & poultry) is positively associated with weight gain and increased abdominal obesity in men and women. [ 15 ]