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It has been suggested that smallpox was a major component of the Plague of Athens that occurred in 430 BCE, during the Peloponnesian Wars, and was described by Thucydides. Galen's description of the Antonine Plague, which swept through the Roman Empire in 165–180 CE, indicates that it was probably caused by smallpox. [13]
Mexico's native population was one of the first to experience a smallpox epidemic, where many succumbed to the disease. In 1520, the first wave of smallpox killed 5–8 million people. From 1545 to 1576, up to 17 million people died from smallpox. This large amount of deaths in the second wave are thought to be the result of hemorrhagic fevers. [5]
1350 BC plague of Megiddo c. 1350 BC Megiddo, land of Canaan: Amarna letters EA 244, Biridiya, mayor of Megiddo complains to Amenhotep III of his area being "consumed by death, plague and dust" Unknown [29] Hittite Plague/"Hand of Nergal" c. 1330 BC Near East, Hittite Empire, Alashiya, possibly Egypt: Unknown, possibly Tularemia.
Others have noted that certain symptoms described, including gastrointestinal hemorrhaging, are not present in current observations of S. Paratyphi C infections. [21] Ultimately, a more definitive proposal for the cause of any of the cocoliztli epidemics of 1545–1548 and 1576–1581 awaits further developments in ancient RNA analysis, and the ...
In Florida alone, an estimated 700,000 Native Americans lived there in 1520, but by 1700 the number was around 2,000. [ 28 ] Some 21st-century climate scientists have suggested that a severe reduction of the indigenous population in the Americas and the accompanying reduction in cultivated lands during the 16th, 17th and 18th centuries may have ...
López de Gómara, Francisco, Hispania Victrix; First and Second Parts of the General History of the Indies, With the Whole Discovery and Notable Things That Have Happened Since They Were Acquired Until the Year 1551, With the Conquest of Mexico and New Spain; Sahagún, Fray Bernardino de.
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The onset of symptoms was sudden, with death often occurring within hours. Sweating sickness epidemics were unique compared with other disease outbreaks of the time: whereas other epidemics were typically urban and long-lasting, cases of sweating sickness spiked and receded very quickly, and heavily affected rural populations. [2]