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  2. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1-adrenergic receptor and has no intrinsic sympathomimetic activity. [37] Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.

  3. Beta blocker - Wikipedia

    en.wikipedia.org/wiki/Beta_blocker

    Beta blockers are known primarily for their reductive effect on heart rate, although this is not the only mechanism of action of importance in congestive heart failure. [17] Beta blockers, in addition to their sympatholytic β 1 activity in the heart, influence the renin–angiotensin system at the kidneys.

  4. Bisoprolol - Wikipedia

    en.wikipedia.org/wiki/Bisoprolol

    Mechanism of action [ edit ] Bisoprolol is cardioprotective because it selectively and competitively blocks catecholamine ( adrenaline ) stimulation of β 1 adrenergic receptors (adrenoreceptors), which are mainly found in the heart muscle cells and heart conduction tissue (cardiospecific), but also found in juxtaglomerular cells in the kidney ...

  5. Onset of action - Wikipedia

    en.wikipedia.org/wiki/Onset_of_action

    A few drugs such as alcohol are absorbed by the lining of the stomach, and therefore tend to take effect much more quickly than the vast majority of oral medications which are absorbed in the small intestine. Gastric emptying time can vary from 0 to 3 hours, [2] and therefore plays a major role in onset of action for orally administered drugs ...

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    Being a topical means MED3000 targets your penis directly and offers a “quick onset of action,” Dr. Pearlman says. “People love spontaneity when it comes to having sex. MED3000’s 10-minute ...

  7. Timolol - Wikipedia

    en.wikipedia.org/wiki/Timolol

    [3] [14] The mechanism of action of timolol is probably the reduction of the formation of aqueous humor [3] in the ciliary body in the eye. It was the first beta blocker approved for topical use in treatment of glaucoma in the United States (1978). [ 15 ]

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  9. Phentolamine - Wikipedia

    en.wikipedia.org/wiki/Phentolamine

    The primary application for phentolamine is for the control of hypertensive emergencies, most notably due to pheochromocytoma. [5]It also has usefulness in the treatment of cocaine-induced cardiovascular complications, where one would generally avoid β-blockers (e.g. metoprolol), as they can cause unopposed α-adrenergic mediated coronary vasoconstriction, worsening myocardial ischemia and ...

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