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The antibiotic, which would be the first new gonorrhea treatment approved in decades, could make it to market by 2025. ... The new zoliflodacin study enrolled 930 men, women and adolescents ...
[67] [68] In 2016, the WHO published new guidelines for treatment, stating "There is an urgent need to update treatment recommendations for gonococcal infections to respond to changing antimicrobial resistance (AMR) patterns of N. gonorrhoeae. High-level resistance to previously recommended quinolones is widespread and decreased susceptibility ...
One promising area is molecular tests, which Hamill says look for genetic markers that can signal a gonorrhea infection is resistant to certain antibiotics so doctors can prescribe the best ...
The removal of fluoroquinolones as a potential treatment left cephalosporins as the only viable antimicrobial option for gonorrhea treatment. Wary of further gonococcal resistance, the CDC's recommendations shifted in 2010 to a dual therapy strategy--cephalosporin with either azithromycin or doxycycline .
Neisseria gonorrhoeae, the bacterium that causes the sexually transmitted infection gonorrhea, has developed antibiotic resistance to many antibiotics. The bacteria was first identified in 1879. [1] In the 1940s effective treatment with penicillin became available, but by the 1970s resistant strains predominated. Resistance to penicillin has ...
New cases of chlamydia and syphilis may be stabilizing in the U.S., while gonorrhea cases have declined for two consecutive years. Alyssa Pointer for The Washington Post via Getty Images
Zoliflodacin (development codes AZD0914 and ETX0914) is an experimental antibiotic that is being studied for the treatment of infection with Neisseria gonorrhoeae (). [1] It has a novel mechanism of action which involves inhibition of bacterial type II topoisomerases. [2]
A study out of the University of York shows that carbon monoxide-releasing molecules could be the key to developing a new antibiotic to treat gonorrhea.