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  2. meta-Chlorophenylpiperazine - Wikipedia

    en.wikipedia.org/wiki/Meta-Chlorophenylpiperazine

    [2] [51] [52] The elimination half-life of mCPP is 4 to 14 hours. [2] mCPP is a metabolite of a variety of other piperazine drugs including trazodone, nefazodone, etoperidone, enpiprazole, mepiprazole, cloperidone, peraclopone, and BRL-15,572. [52] [additional citation(s) needed] It is formed by dealkylation via CYP3A4. [52]

  3. Trazodone - Wikipedia

    en.wikipedia.org/wiki/Trazodone

    Trazodone has a minor active metabolite known as meta-chlorophenylpiperazine (mCPP), and this metabolite may contribute to some degree to the pharmacological properties of trazodone. [11] [110] In contrast to trazodone, mCPP is an agonist of various serotonin receptors. [111]

  4. Substituted piperazine - Wikipedia

    en.wikipedia.org/wiki/Substituted_piperazine

    Trazodone, nefazodone, mepiprazole, and others produce mCPP as a metabolite. para-Substituted. 4-Chlorophenylpiperazine (pCPP) 4-Fluorophenylpiperazine (pFPP)

  5. Caitlin Clark Responds After Megyn Kelly Attacks Her Comments ...

    www.aol.com/caitlin-clark-responds-megyn-kelly...

    Jason Mendez/Getty; Noam Galai/Getty . Caitlin Clark at TIME dinner in New York City on Dec. 11, 2024; Megyn Kelly at SiriusXM Studios on May 20, 2024

  6. 2,3-Dichlorophenylpiperazine - Wikipedia

    en.wikipedia.org/wiki/2,3-Dichlorophenylpiperazine

    It is both a precursor in the synthesis of aripiprazole and one of its metabolites. [1] [2] It is unclear whether 2,3-DCPP is pharmacologically active as a serotonin receptor agonist similar to its close analogue 3-chlorophenylpiperazine (mCPP), though it has been shown to act as a partial agonist of the dopamine D 2 and D 3 receptors. [3]

  7. Drinkable Mayonnaise Is Now a Thing - AOL

    www.aol.com/drinkable-mayonnaise-now-thing...

    A convenience store chain is putting Nomu Mayo, its new drinkable mayonnaise, through a "test sale period" to see how customers respond.

  8. Lawyer for Mass. Mom Who Killed Her 3 Children Before ... - AOL

    www.aol.com/lawyer-mass-mom-killed-her-205741308...

    Prosecutors allege that Lindsay Clancy committed premeditated murder when she killed her three children in her Duxbury, Mass., home before attempting to die by suicide

  9. Serotonin antagonist and reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin_antagonist_and...

    These drugs act as antagonists or inverse agonists of the 5-HT 2A, α 1-adrenergic, and H 1 receptors, as partial agonists of the 5-HT 1A receptor, [3] and as inhibitors of the transporters. mCPP is an antagonist of the 5-HT 2B receptor, an agonist of the 5-HT 1A, [3] 5-HT 2C, and 5-HT 3 receptors, [4] [5] and acts as a partial agonist of the ...

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