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Curex is an American telehealth company specializing in immunology, specifically the diagnosis and treatment of allergies, including the prescription and delivery of allergy immunotherapy. [1] The company was founded by Gene Kakaulin and Charles Jacoby in 2020 [ 2 ] and is headquartered in New York City. [ 3 ]
Sublingual immunotherapy involves putting drops or a tablet of allergen extracts under the tongue, which are then absorbed through the lining of the mouth. Sublingual immunotherapy has been demonstrated to be effective against rhinoconjunctivitis and asthma symptoms. [15] This effectiveness, however, varies depending on the type of allergen. [15]
In 1992, ALK and Abello merged. In the 1990s, ALK was the first company to launch sublingual immunotherapy drops (allergy immunotherapy administered as droplets under the tongue). In recent years, ALK's research and development strategy has been focused on introducing a range of sublingual immunotherapy tablets (SLIT-tablets).
Treatment can be given as an injection, tablet, sprays or sublingual drops. The gradual increase of allergen causes the immune system to become less sensitive to the substance ( desensitization ), reducing symptoms during future exposures to the allergen, and possibly preventing new allergies.
The sublingual route may also be used for vaccines against various infectious diseases. Thus, preclinical studies have found that sublingual vaccines can be highly immunogenic and may protect against influenza virus [4] [5] and Helicobacter pylori, [6] but sublingual administration may also be used for vaccines against other infectious diseases.
Allergen immunotherapy is the only treatment that alters the disease mechanism. [27] Immunotherapy can be administered orally (as sublingual tablets [28] or sublingual drops), or by injections under the skin (subcutaneous). [29] Subcutaneous immunotherapy is the most common form and has the largest body of evidence supporting its effectiveness ...
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"SC" can be mistaken for "SL," meaning sublingual. See also SQ: sem. semen seed s.i.d. semel in die: once a day used exclusively in veterinary medicine sig. signa, signetur: write (write on the label) s̄ sine: without (usually written with a bar on top of the s) sing. singulorum: of each SL, s.l. sub lingua: sublingually, under the tongue SOB