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This is typically secondary to stroke, injury, or cardiac arrest due to heart attack. Most ischemic neurons that die do so due to the activation of chemicals produced during and after ischemia. [2] The ischemic cascade usually goes on for two to three hours but can last for days, even after normal blood flow returns. [3]
The brain damage caused by a stroke can lead to serious problem such as: ... increasing your stroke risk. Heart disease: ... Study on BrainHQ training and stroke recovery: Neurology.
Also known as 'effort angina', this refers to the classic type of angina related to myocardial ischemia.A typical presentation of stable angina is that of chest discomfort and associated symptoms precipitated by some activity (running, walking, etc.) with minimal or non-existent symptoms at rest or after administration of sublingual nitroglycerin. [11]
Ischemia results in tissue damage in a process known as ischemic cascade. The damage is the result of the build-up of metabolic waste products, inability to maintain cell membranes , mitochondrial damage, and eventual leakage of autolyzing proteolytic enzymes into the cell and surrounding tissues.
Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re-+ perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).
Coronary Artery Disease. Coronary artery disease, or coronary heart disease, is the most common type of heart disease. It occurs when fatty deposits called plaques build up in your arteries ...
Coronary artery disease (CAD) occurs when fatty substances, known as plaques, adhere to the walls of coronary arteries supplying the heart, narrowing them and constricting blood flow, a process known as atherosclerosis, the most common cause of coronary ischemia. [25] Angina may start to occur when the vessel is 70% occluded. [9]
Variant angina is caused by vasospasm, a narrowing of the coronary arteries due to contraction of the heart's smooth muscle tissue in the vessel walls. [3] In comparison, stable angina is caused by the permanent occlusion of these vessels by atherosclerosis, which is the buildup of fatty plaque and hardening of the arteries. [4]