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Ferrous iron is then absorbed in the small intestine where it is oxidized into its ferric iron (Fe 3+) form before being released into the bloodstream. [4] Free iron in the blood is toxic to the body as it disrupts normal cell function, damaging organs such as the liver, stomach, and cardiovascular system. [ 4 ]
Common side effects include constipation, abdominal pain, dark stools, and diarrhea. [14] Other side effects, which may occur with excessive use, include iron overload and iron toxicity. [11] [13] Ferrous salts used as supplements by mouth include ferrous fumarate, ferrous gluconate, ferrous succinate, and ferrous sulfate. [13]
Iron(II) fumarate, also known as ferrous fumarate, is the iron(II) salt of fumaric acid, occurring as a reddish-orange powder, used to supplement iron intake. It has the chemical formula C 4 H 2 Fe O 4 .
Examples of iron preparation include ferrous sulfate, ferrous gluconate, and ferrous fumarate. It can be administered orally, and by intravenous injection, or intramuscular injection. [1] Early Iron Supplement for Anemia. Iron preparation stimulates red blood cell production.
Some preparations of EE/LNG additionally contain an iron supplement in the form of ferrous bisglycinate or ferrous fumarate. [4] Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems. [3]
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Some preparations of EE/NET additionally contain an iron supplement in the form of ferrous fumarate. [3] Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems. [2] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots.
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