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FimH is a bacterial adhesin that helps bacteria such as Escherichia coli to bind to host cells and their receptors (here: the human proteins CD48 and TLR4, or mannose residues). [ 4 ] Most fimbria of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin.
An S-layer (surface layer) is a cell surface protein layer found in many different bacteria and in some archaea, where it serves as the cell wall. All S-layers are made up of a two-dimensional array of proteins and have a crystalline appearance, the symmetry of which differs between species.
Bacteria produce various adhesins including lipoteichoic acid, trimeric autotransporter adhesins and a wide variety of other surface proteins to attach to host tissue. Capsules, made of carbohydrate, form part of the outer structure of many bacterial cells including Neisseria meningitidis.
The glycocalyx (pl.: glycocalyces or glycocalyxes), also known as the pericellular matrix and cell coat, is a layer of glycoproteins and glycolipids which surround the cell membranes of bacteria, epithelial cells, and other cells. [1] Animal epithelial cells have a fuzz-like coating on the external surface of their plasma membranes.
Bacteria often produce capsules made of proteins or sugars that coat their cells and interfere with phagocytosis. [107] Some examples are the K5 capsule and O75 O antigen found on the surface of Escherichia coli , [ 111 ] and the exopolysaccharide capsules of Staphylococcus epidermidis . [ 112 ]
A leukocidin is a type of cytotoxin created by some types of bacteria (Staphylococcus).It is a type of pore-forming toxin.The model for pore formation is step-wise. First, the cytotoxin's "S" subunit recognizes specific protein-containing receptors, or an integrin on the host cell's surface.
The general secretion (Sec) involves secretion of unfolded proteins that first remain inside the cells. In Gram-negative bacteria, the secreted protein is sent to either the inner membrane or the periplasm. But in Gram-positive bacteria, the protein can stay in the cell or is mostly transported out of the bacteria using other secretion systems.
M protein is a virulence factor that can be produced by certain species of Streptococcus. [1] Viruses, parasites and bacteria are covered in protein and sugar molecules that help them gain entry into a host by counteracting the host's defenses. One such molecule is the M protein produced by certain streptococcal bacteria.