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They are a characteristic of lupus erythematosus, [3] but also found in similar connective tissue disorders or some autoimmune diseases like in severe rheumatoid arthritis. LE cells can be observed in drug-induced lupus, for example, following treatment with methyldopa. [4] The LE cell was discovered in bone marrow in 1948 by Malcolm McCallum ...
The Great Impersonator is the fifth studio album by American singer Halsey, released on October 25, 2024, by Columbia Records, marking her first release with the label.Her first full-length release since If I Can't Have Love, I Want Power (2021), Halsey conceived it as a confessional concept album believing it would be her last project after being diagnosed with lupus and a T cell ...
The LE cell, it was determined, was a part of an anti-nuclear antibody (ANA) reaction; the body produces antibodies against its own tissue. This discovery led to one of the first definitive tests for lupus since LE cells are found in approximately 60% of all people diagnosed with lupus. [168]
In diagnostic pathology, a hematoxylin body, or LE body, is a dense, homogeneous, basophilic particle, easily stainable with hematoxylin. It consists of degraded nuclear material from an injured cell, along with autoantibodies and a limited amount of cytoplasm. [1] [2] [3] Hematoxylin bodies occur in systemic lupus erythematosus.
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]
Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs.These drugs cause an autoimmune response (the body attacks its own cells) producing symptoms similar to those of systemic lupus erythematosus (SLE).
This is the discography of Soft Cell, a British synth-pop duo consisting of Marc Almond and Dave Ball who rose to prominence in the early 1980s. The duo broke up in 1984 after releasing four albums, but reunited in the early 2000s for a series of live dates and released an album of new material in 2002.