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The 12 E. coli LTEE populations on June 25, 2008. [1]The E. coli long-term evolution experiment (LTEE) is an ongoing study in experimental evolution begun by Richard Lenski at the University of California, Irvine, carried on by Lenski and colleagues at Michigan State University, [2] and currently overseen by Jeffrey Barrick at the University of Texas at Austin. [3]
Griffith's experiment discovering the "transforming principle" in Streptococcus pneumoniae (pneumococcal) bacteria.. Griffith's experiment, [1] performed by Frederick Griffith and reported in 1928, [2] was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation.
The Luria–Delbrück experiment (1943) (also called the Fluctuation Test) demonstrated that in bacteria, genetic mutations arise in the absence of selective pressure rather than being a response to it. Thus, it concluded Darwin's theory of natural selection acting on random mutations applies to bacteria as well as to more complex organisms.
Horizontal gene transfer is the primary mechanism for the spread of antibiotic resistance in bacteria, [8] [5] [9] [10] and plays an important role in the evolution of bacteria that can degrade novel compounds such as human-created pesticides [11] and in the evolution, maintenance, and transmission of virulence. [12]
Science aid: Bacterial Growth High school (GCSE, Alevel) resource. Microbial Growth, BioMineWiki Archived September 20, 2011, at the Wayback Machine; From the Wolfram Demonstrations Project — requires CDF player (free): The Final Number of Bacterial Cells; Simulating Microbial Count Records with an Expanded Fermi Solution Model
[3] [5] Todesco worked in the lab after school, spent March breaks there and also skipped her grade 12 classes (at Queen Elizabeth Junior Senior High School) to develop this project while attending high school. [1] Her bacteria-infused sand filtration bioreactor were able to degrade oil sand waste 14 times faster than current methods. [5] [6]
Serial passage is the process of growing bacteria or a virus in iterations. For instance, a virus may be grown in one environment, and then a portion of that virus population can be removed and put into a new environment.
Due to its ease of culture and fast doubling, it was used in the early microbiology experiments; however, bacteria were considered primitive and pre-cellular and received little attention before 1944, when Avery, Macleod and McCarty demonstrated that DNA was the genetic material using Salmonella typhimurium, following which Escherichia coli was ...