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Antisialagogues are drugs or substances that decrease the flow rate of saliva and their effect is opposite to that of sialagogues. [1] Their origin may be both natural and synthetic. Anticholinergics generally have antisialagogue effects, and most produce some level of sedation, both being advantageous in surgical procedures. [2]
It has also been defined as increased amount of saliva in the mouth, which may also be caused by decreased clearance of saliva. [ 4 ] Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting.
Sialometery can yield measures of stimulated salivary flow or unstimulated salivary flow. Stimulated salivary flow rate is calculated using a stimulant such as 10% citric acid dropped onto the tongue, and collection of all the saliva that flows from one of the parotid papillae over five or ten minutes. Unstimulated whole saliva flow rate more ...
Metformin is a medication in a class of compounds called biguanides, according to the U.S. National Library of Medicine. These medications reduce the amount of glucose the body absorbs from food ...
Artificial saliva also contributes to oral health maintenance by promoting enamel defence against acidic erosion. In individuals with a high intake of soft drinks or a high vomiting frequency and a decrease in saliva flow, artificial saliva can help improve the clearance time of acids and reduce the chance of dental erosion.
Exercise helps promote a healthy body weight, which can prevent excess pressure on the lower esophageal sphincter. And if you smoke (another risk factor for reflux), exercise is especially beneficial.
Xerostomia, or a decrease in saliva flow, can be a side effect of many drugs, which, in turn, can lead to the development of taste disturbances such as dysgeusia. [39] Patients can lessen the effects of xerostomia with breath mints, sugarless gum, or lozenges; or physicians can increase saliva flow with artificial saliva or oral pilocarpine. [39]
As the chart below shows, traces of drugs like LSD, morphine, heroin, amphetamines, and alcohol all remain in the blood for just 12 hours or less: bi_graphics_how long drugs stay in your blood ...