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It has also been defined as increased amount of saliva in the mouth, which may also be caused by decreased clearance of saliva. [ 4 ] Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting.
Antisialagogues are drugs or substances that decrease the flow rate of saliva and their effect is opposite to that of sialagogues. [1] Their origin may be both natural and synthetic. Anticholinergics generally have antisialagogue effects, and most produce some level of sedation, both being advantageous in surgical procedures. [2]
Stomach pain or tummy troubles are among the most common ailments that affect children and adults alike. Feelings of bloating, cramping, constipation or nausea often occur because of something ...
Scopolamine, also known as hyoscine, [9] or Devil's Breath, [10] is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness [11] and postoperative nausea and vomiting. [12] [1] It is also sometimes used before surgery to decrease saliva. [1]
Lorazepam (Ativan) is said to be very good as an adjunct treatment for nausea along with first line medications such as Compazine. [citation needed] Anticholinergics. Hyoscine (also known as scopolamine) Atropine; Steroids. Dexamethasone (Decadron) is given in low dose at the onset of a general anesthetic as an effective antiemetic.
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
Unstimulated whole saliva flow rate more closely correlates with symptoms of xerostomia than stimulated salivary flow rate. [1] Sialography involves introduction of radio-opaque dye such as iodine into the duct of a salivary gland. [1] It may show blockage of a duct due to a calculus. Salivary scintiscanning using technetium is rarely used.
Salivary stones (sialolith) may be evident with cystic dilation of the salivary ducts and periductal fibrosis. Mucus extravasation may also be observed. Common observations of chronic sialadenitis include chronic inflammatory infiltrate (lymphocytes, plasma cells and macrophages), fibrosis, acinar atrophy, and mucous cell metaplasia of the ...