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Mechanism of self-amplifying mRNA (saRNA) used for antigen production. The ORF encoding the antigen can also be substituted with a protein for use in protein replacement therapy. This sequence encodes the protein of interest, used as an antigen in the case of vaccines or for protein replacement therapies. The gene of interest replaces the viral ...
To identify an saRNA that can activate a gene of interest, several saRNAs need to be designed within a 1- to 2-kbp promoter region by following a set of rules [3] [4] and tested in cultured cells. In some reports, saRNAs are designed in such a way to target non-coding transcripts that overlap the promoter sequence of a protein coding gene.
Bakeries can provide a wide range of cake designs such as sheet cakes, layer cakes, wedding cakes, tiered cakes, etc. Other bakeries may specialize in traditional or hand-made types of baked products made with locally milled flour, without flour bleaching agents or flour treatment agents, baking what is sometimes referred to as artisan bread. [1]
Corn syrup is a sweet, viscous syrup made from refined cornstarch and used as a liquid sweetener or thickener in candy, pies, jams and jellies, and even beer. At the grocery store, you’ll find ...
Although the Easy Bake Oven technically was not the first working toy oven for children, the product grew in popularity due to use of a light bulb as a heat source -- in addition to the vast array ...
Whether you’re making cookies, cakes, breads, or brownies, you’d be hard pressed to find a baking recipe that doesn’t include a rising agent. The secret to soft and fluffy treats is the ...
Breads, cakes and patisserie for sale at the Berman's Bakery retail bread shop in Givat Shaul, Jerusalem Bread baking in a traditional oven. This is a list of notable bakeries. A bakery is an establishment that produces and sells flour-based food baked in an oven such as bread, cakes, pastries, and pies. [1]
The dough is generally prepared with flour, eggs, sugar, butter (or margarine or cooking oil), and a flavoring such as vanilla (or sometimes cocoa, grated lemon rind, rose water, or orange blossom water); sometimes milk is used in the dough; and usually a leavener such as baking powder or baking soda is added as well. The dough is then mixed ...