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Lyme disease can be tricky to diagnose, given that the symptoms can mimic those of other illnesses, says Thomas Russo, M.D., professor and chief of infectious disease at the University at Buffalo ...
Lyme disease, also known as Lyme borreliosis, is a tick-borne disease caused by species of Borrelia bacteria, transmitted by blood-feeding ticks in the genus Ixodes. [4] [9] [10] The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. [1]
Lyme disease is caused by infected black-legged (or deer) ticks and symptoms of the disease may vary, depending on how long it takes to discover the signs. Show comments Advertisement
Lyme disease symptoms. According to Mayo Clinic, Lyme disease symptoms commonly occur in stages. Common stage 1 symptoms that show up 3 to 30 days after a tick bite include:
This rash was known as erythema chronicum migrans, the skin rash found in early-stage Lyme disease. [ 18 ] In the 1920s, French physicians Garin and Bujadoux described a patient with meningoencephalitis, painful sensory radiculitis, and erythema migrans following a tick bite, and they postulated the symptoms were due to a spirochetal infection.
The genomic variations have direct implications on the clinical symptoms of tick-borne Lyme disease. For example, B. burgdorferi s.s.’s tick-borne Lyme disease may manifest with arthritis-like symptoms. [9] In contrast, B. garinii’s tick-borne Lyme disease may cause an infection of the central nervous system. [9]
If a bacterial infection goes untreated for too long, it can make you really sick. Often, this results in a fever, but chills sans fever have been reported in people with a range of infections, too.
Chronic Lyme disease is distinct from untreated late-stage Lyme disease, which can cause arthritis, peripheral neuropathy and/or encephalomyelitis. Chronic Lyme disease is also distinct from post-treatment Lyme disease syndrome (PTLDS) when symptoms linger after standard antibiotic treatments.
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