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Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
NSAIDS are a nonspecific medication used for abortion of migraines due to their analgesic properties. They can be used for mild to moderate migraines, but are less effective against severe migraines. [8] Similar to the triptans and ergots alkaloids, their use should be limited to less than 10x per month to reduce MOH.
A meta-analysis of 53 clinical trials has shown that all triptans are effective for treating migraine at marketed doses and that naratriptan, although less effective than sumatriptan and rizatriptan was more effective than placebo in reducing migraine symptoms at two hours [3] and efficacy was demonstrated in almost two thirds of subjects after four hours of treatment.
Further, women are more likely than men to develop chronic pain during their reproductive years. UVA’s new research may help explain why. The findings suggest that progesterone receptors in the ...
Methylergometrine is sometimes used for both prevention [6] and acute treatment [7] of migraine. It is an active metabolite of methysergide. [8] In the treatment of cluster headaches, methylergometrine has been initiated at a dose of 0.2 mg/day, rapidly increased to 0.2 mg three times per day, and increased to a maximum of 0.4 mg three times per day.
Part of creating a treatment strategy for migraine involves reducing and preventing central sensitization because when that kicks in, "it's harder to treat migraines and certain medications don't ...
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