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Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
Subcutaneous and intramuscular injections are generally more effective than the nasal spray and can be self-administered by patients. [8] Intravenous injection is considered very effective for severe migraine or status migrainosus. DHE is also used in the treatment of medication overuse headache. [9]
CGRP antagonists can be used for both acute migraine treatment as well as prophylactically. [14] CGRP is a neuropeptide which is thought to induce migraines via vasodilation of cranial arteries. [14] CGRP can also release inflammatory agents and cause nervous system sensitization. [14]
Newer approaches: C.G.R.P. antibodies, which are once-monthly injections, and Botox injections help block the pathways in the brain that are used during a migraine attack.
Migraine causes a "severe throbbing or pounding headache with light or sound sensitivity and sometimes nausea," noted Dr. Timothy A. Collins, chief of the Division of Headache and Pain at Duke ...
A migraine attack often causes severe throbbing pain or a pulsing sensation, usually on one side of the head. ... “Without treatment, migraine can interfere with your ability to function, study ...
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