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  2. Lupus anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Lupus_anticoagulant

    As a further confirmation, a second test with the addition of excess phospholipid will correct the prolongation (conceptually known as "phospholipid neutralization"), confirming the diagnosis of a lupus anticoagulant. Lupus-sensitive aPTT, of which many variants exist, but have the common feature of having a greater sensitivity of becoming ...

  3. Kaolin clotting time - Wikipedia

    en.wikipedia.org/wiki/Kaolin_clotting_time

    Kaolin clotting time (KCT) is a sensitive test to detect lupus anticoagulants. [2] There is evidence that suggests it is the most sensitive test for detecting lupus anticoagulants. [3] It can also detect factor VIII inhibitors but is sensitive to unfractionated heparin as well. [4]

  4. Dilute Russell's viper venom time - Wikipedia

    en.wikipedia.org/wiki/Dilute_Russell's_viper...

    Russell's viper, Daboia russelii Dilute Russell's viper venom time (dRVVT) is a laboratory test often used for detection of lupus anticoagulant (LA). It is an assessment of the time for blood to clot in the presence of a diluted amount of venom from Russell's viper (Daboia russelii), a highly venomous snake native to the Indian subcontinent and named after the herpetologist Patrick Russell.

  5. Partial thromboplastin time - Wikipedia

    en.wikipedia.org/wiki/Partial_thromboplastin_time

    The partial thromboplastin time (PTT), also known as the activated partial thromboplastin time (aPTT or APTT), is a blood test that characterizes coagulation of the blood.A historical name for this measure is the Kaolin-cephalin clotting time (KCCT), [1] reflecting kaolin and cephalin as materials historically used in the test.

  6. Mixing study - Wikipedia

    en.wikipedia.org/wiki/Mixing_study

    Mixing studies are tests performed on blood plasma of patients or test subjects to distinguish factor deficiencies from factor inhibitors, such as lupus anticoagulant, or specific factor inhibitors, such as antibodies directed against factor VIII. [1] Mixing studies are screening tests widely performed in coagulation laboratories.

  7. Clotting time - Wikipedia

    en.wikipedia.org/wiki/Clotting_time

    Clotting time is a general term for the time required for a sample of blood to form a clot, or, in medical terms, coagulate.The term "clotting time" is often used when referring to tests such as the prothrombin time (PT), activated partial thromboplastin time (aPTT or PTT), activated clotting time (ACT), thrombin time (TT), or Reptilase time.

  8. Activated protein C resistance test - Wikipedia

    en.wikipedia.org/wiki/Activated_protein_C...

    The aPTT-based APC resistance test involves a modified aPTT test performed in the presence and absence of activated protein C (APC). [1] [5] The ratio of these aPTT values is calculated and is called the APC sensitivity ratio (APCsr) or simply APC ratio (APCr). [1] [5] This ratio is inversely related to the degree of APC resistance. [7]

  9. Anti-thrombin antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-thrombin_antibodies

    Anti-thrombin antibodies are autoantibodies directed against thrombin that may constitute a fraction of lupus anticoagulant and are seen an increased levels in systemic lupus erythematosus. crystal structure of thrombin .

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