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A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion [1]) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. [2] The axons of dorsal root ganglion neurons are known as afferents.
The root emerges from the posterior part of the spinal cord and travels to the dorsal root ganglion. The dorsal root ganglia contain the pseudo-unipolar cell bodies of the nerve fibres which travel from the ganglia through the root into the spinal cord. The lateral division of the dorsal root contains lightly myelinated and unmyelinated fibres ...
Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating nerve root pain which is aggravated by coughing, and features of sensory ataxia with ocular ...
The dorsal root ganglion contains cell bodies for sensory nerves including large, myelinated Aβ fibers which carry proprioception and tactile touch sensation to the brain via the dorsal column–medial lemniscus pathway and small, unmyelinated C fibers which carry thermal and pain sensation to the brain via the spinothalamic tract. [2]
A dorsal root ganglion (DRG) from a chicken embryo (around stage of day 7) after incubation overnight in NGF growth medium stained with anti-neurofilament antibody. Note the axons growing out of the ganglion. A ganglion (pl.: ganglia) is a group of neuron cell bodies in the peripheral nervous system.
The body is situated in the dorsal root ganglion, with one axon traveling peripherally to tissue, and one traveling into the dorsal column. On the right is a bipolar neuron. When an action potential is generated by a mechanoreceptor in the tissue, the action potential will travel along the peripheral axon of the first-order neuron.
The cell body of a pseudounipolar neuron is located within a dorsal root ganglion. [2] The axon leaves the cell body (and out of the dorsal root ganglion) into the dorsal root, where it splits into two branches. The central branch goes to the dorsal columns of the spinal cord, where it forms synapses with other neurons.
The ganglion of the sensory nerves, which are similar in structure to the dorsal root ganglion of the spinal cord, include: [13] The trigeminal ganglia of the trigeminal nerve (V), which occupies a space in the dura mater called Meckel's cave. This ganglion contains only the sensory fibres of the trigeminal nerve.