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A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion [1]) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. [2] The axons of dorsal root ganglion neurons are known as afferents.
The dorsal root of spinal nerve (or posterior root of spinal nerve or sensory root) [1] is one of two "roots" which emerge from the spinal cord. It emerges directly from the spinal cord, and travels to the dorsal root ganglion. Nerve fibres with the ventral root then combine to form a spinal nerve. The dorsal root transmits sensory information ...
The body is situated in the dorsal root ganglion, with one axon traveling peripherally to tissue, and one traveling into the dorsal column. On the right is a bipolar neuron . When an action potential is generated by a mechanoreceptor in the tissue , the action potential will travel along the peripheral axon of the first-order neuron.
Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating nerve root pain which is aggravated by coughing, and features of sensory ataxia with ocular ...
Dorsal root ganglion neurons differentiate from neural crest progenitors. As the dorsal and ventral column cells proliferate, the lumen of the neural tube narrows to form the small central canal of the spinal cord. [16] The alar plate and the basal plate are separated by the sulcus limitans. Additionally, the floor plate also secretes netrins.
The posterior thoracic nucleus is a major relay center for unconscious proprioception.Sensory information from muscle spindles and tendon organs is carried by axons of larger neurons in dorsal root ganglia, which synapse onto neurons in the spinal cord including the posterior thoracic nucleus.
Just outside the spinal cord, thousands of afferent neuronal cell bodies are aggregated in a swelling in the dorsal root known as the dorsal root ganglion. [1] [2] All of the axons in the dorsal root, which contains afferent nerve fibers, are used in the transduction of somatosensory information.
The dorsal root ganglion contains cell bodies for sensory nerves including large, myelinated Aβ fibers which carry proprioception and tactile touch sensation to the brain via the dorsal column–medial lemniscus pathway and small, unmyelinated C fibers which carry thermal and pain sensation to the brain via the spinothalamic tract. [2]