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Sirtex Medical Limited is a medical device firm that offers radioactive treatment for inoperable liver cancer called SIR-Spheres microspheres. [1] Sirtex was founded in 1997 in Australia and today has offices and production facilities in the U.S. , Australia , Germany , and Singapore .
SIR-Spheres microspheres are used to treat patients with unresectable liver cancer. These are mostly patients with hepatocellular carcinoma (HCC), metastatic colorectal cancer (mCRC), or metastatic neuroendocrine tumours (mNET). [1] Therapy goals are local disease control, downstaging to resection, bridging to transplantation, and extended ...
SIR-Spheres were CE-marked as a medical device in 2002, for treating advanced inoperable liver tumors, and Theraspheres in 2014, for treating hepatic neoplasia. [37] QuiremSpheres (PLLA 166 Ho microspheres) received their CE mark in April 2015 for treating unresectable liver tumors and are currently only available for the European market. [37] [41]
TheraSphere is a radiotherapy treatment for hepatocellular carcinoma (HCC) that consists of millions of microscopic, radioactive glass microspheres (20–30 micrometres in diameter) being infused into the arteries that feed liver tumors.
Yttrium-90 is produced by the nuclear decay of strontium-90 which has a half-life of nearly 29 years and is a fission product of uranium used in nuclear reactors. As the strontium-90 decays, chemical high-purity separation is used to isolate the yttrium-90 before precipitation.
Varian Medical Systems is an American radiation oncology treatments and software maker based in Palo Alto, California.Their medical devices include linear accelerators (LINACs) and software for treating cancer and other medical conditions with radiotherapy, radiosurgery, proton therapy, and brachytherapy.
Sirtuin 6 (SIRT6 or Sirt6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene. [5] [6] [7] In laboratory research, SIRT6 appears to function in multiple molecular pathways related to aging, including DNA repair, telomere maintenance, glycolysis and inflammation. [5]
Incision and excision of skull, brain, and cerebral meninges Cranial puncture() Cisternal punctur() Ventriculopuncture through previously implanted cathete() Other cranial punctur