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In 2021, Demasi co-authored a paper with Robert DuBroff challenging statin therapy. [16] As of 2022, Demasi is a writer for the Brownstone Institute, an organization that has been criticized by medical experts for spreading misinformation against vaccines. [17] [18]
Stephen T. Sinatra (15 October 1946 –19 June 2022) was a board-certified cardiologist specializing in integrative medicine.He was also a certified bioenergetic psychotherapist.
New research finds that many people currently taking statins to lower cholesterol may not actually need this medication. An analysis, published in JAMA Internal Medicine , investigates how statin ...
The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP). JUPITER was the first clinical trial to indicate that statin therapy may provide benefit to patients with low-to-normal LDL levels and no known cardiovascular disease.
New research from the University of Hong Kong found that statins effectively lowered the risk of cardiovascular and all-cause mortality among adults 60 years of age and older — including people ...
An avid runner, she is thrilled to be pain free, but she is stymied about how to manage her cholesterol. “I feel better than I have in 30 years, but my cholesterol numbers are going up,” Kim said.
Statins are a competitive antagonists of HMG CoA, as they directly compete with the endogenous substrate for the active site cavity of HMGR. Statins are also noncompetitive with the cosubstrate NADPH (nicotinamide adenine dinucleotide phosphate). [5] By blocking the HMGR enzyme they inhibit the synthesis of cholesterol via the mevalonate pathway.
Statins can be used in combination with lifestyle changes to help keep cholesterol in a healthy range. For example, people may minimize their saturated fat intake and increase their physical ...