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MALT lymphoma (also called MALToma) is a form of lymphoma involving the mucosa-associated lymphoid tissue (MALT), frequently of the stomach, but virtually any mucosal site can be affected. It is a cancer originating from B cells in the marginal zone of the MALT.
About 80% of MALT lymphomas completely regress with eradication therapy. [6] Radiation treatment for H. pylori–negative gastric malt lymphoma, has a high success rate, 90% or better after 5 years. Second line therapy for MALT lymphomas is usually chemotherapy with a single agent, and complete response rates of greater than 70% have been ...
It may be the site of lymphomas, usually a non-Hodgkin lymphoma. A specific entity is the marginal zone B-cell lymphoma (a subtype of which is termed MALT lymphoma). Certain subtypes of marginal zone B cell lymphomas such as those occurring in the stomach are commonly caused by Helicobacter pylori infection. [4]
Extranodal marginal zone lymphomas (EMZLs) are a form of MZL [9] in which malignant marginal zone B-cells initially infiltrate MALT tissues of the stomach (50-70% of all EMZL) or, less frequently, the esophagus, small intestine, large intestine, rectum, conjunctiva of the eye, nasal passages, pharynx, lung bronchi, vulva, vagina, skin, breast, thymus gland, meninges (i.e. membranes) that ...
Stomach cancer, Marginal zone B-cell lymphoma of the stomach, and bile duct cancer [2] [5] [6] Helicobacter salomonis: Gastric MALT lymphoma. [2] Helicobacter suis: Gastric MALT lymphoma. [2] Mycoplasma spp Stomach, colon, ovarian, and lung cancers (particularly M. fermentans, M. penetrans, M. hyorhinis). [2] Neisseria gonorrhoeae
MALT lymphoma is a cancer of the mucosa-associated lymphoid tissue, usually in the stomach. Gastrointestinal stromal tumors represent from 1% to 3% of gastrointestinal malignancies. Cancers of the biliary tree, including cholangiocarcinoma.
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Gut-associated lymphoid tissue (GALT) [1] is a component of the mucosa-associated lymphoid tissue (MALT) which works in the immune system to protect the body from invasion in the gut. Owing to its physiological function in food absorption, the mucosal surface is thin and acts as a permeable barrier to the interior of the body.
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