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  2. Clopidogrel - Wikipedia

    en.wikipedia.org/wiki/Clopidogrel

    Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent ( dual antiplatelet therapy ). [ 10 ]

  3. Adenosine diphosphate receptor inhibitor - Wikipedia

    en.wikipedia.org/wiki/Adenosine_diphosphate...

    The thiol forms a disulfide bridge to a cysteine in P2Y 12 receptor and thus binds irreversibly to the P2Y 12 receptor. Clopidogrel is suggested to bind covalently to CYS17 or CYS270 of the P2Y 12 receptor and therefore blocking the binding of the agonist. [18]

  4. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    Blank samples taken before administration are important in determining background and ensuring data integrity with such complex sample matrices. Much attention is paid to the linearity of the standard curve; however it is common to use curve fitting with more complex functions such as quadratics since the response of most mass spectrometers is ...

  5. Luigi Mangione Allegedly Considered Using Bomb to Murder CEO ...

    www.aol.com/luigi-mangione-allegedly-considered...

    Luigi Mangione, who authorities accuse of murdering UnitedHealthcare CEO Brian Thompson, allegedly wrote in a notebook that he considered bombing Manhattan to carry out the killing but did not ...

  6. Wealth strategies that used to be reserved for billionaires ...

    www.aol.com/wealth-strategies-used-reserved...

    Industry stalwarts like Fidelity and upstarts like Envestnet also want a piece of the action. Kapila said the need to compete on scale and fees required Parametric's technology to be as efficient ...

  7. Plavix - Wikipedia

    en.wikipedia.org/?title=Plavix&redirect=no

    From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) the international nonproprietary name (INN).

  8. College football games today: How to watch, stream Saturday's ...

    www.aol.com/college-football-games-today-watch...

    With the new, expanded 12-team playoff this year, a conference championship has never been more important. Five automatic bids are doled out to the five highest-ranking conference champs, meaning ...

  9. Prasugrel - Wikipedia

    en.wikipedia.org/wiki/Prasugrel

    Prasugrel is a member of the thienopyridine class of ADP receptor inhibitors, like ticlopidine (trade name Ticlid) and clopidogrel (trade name Plavix). These agents reduce the aggregation ("clumping") of platelets by irreversibly binding to P2Y 12 receptors. Prasugrel inhibits platelet aggregation more rapidly, more consistently, and to a ...