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Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent ( dual antiplatelet therapy ). [ 10 ]
When ticlopidine and clopidogrel were first brought to the market, ticlodipine in 1978 and clopidogrel in 1998, the mechanism of action of these two major antithrombotic drugs was not fully understood. What had been shown was that they were potent inhibitors of ADP-induced platelet aggregation, but the P2Y 12 receptor had not been identified.
From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) the international nonproprietary name (INN).
And the action will wrap up Monday, when either the Minnesota Vikings travel to face the Los Angeles Rams. Here's the schedule for the wild-card round and beyond: NFL playoff schedule: Wild-card games
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Prasugrel is a member of the thienopyridine class of ADP receptor inhibitors, like ticlopidine (trade name Ticlid) and clopidogrel (trade name Plavix). These agents reduce the aggregation ("clumping") of platelets by irreversibly binding to P2Y 12 receptors. Prasugrel inhibits platelet aggregation more rapidly, more consistently, and to a ...
The San Francisco 49ers on Monday suspended linebacker De'Vondre Campbell for the final three games of the regular season for refusing to play Thursday night against the Los Angeles Rams.. Niners ...
It took outcry from affected communities, medical professionals, and activists before the U.S. and international health community took major action to combat the growing epidemic.