Search results
Results from the WOW.Com Content Network
The peptides can be specially designed for specificity. A single peptide vaccine can be designed to have multiple epitopes to generate immune responses for several diseases. The vaccines only contain a short peptide chain, so they are less like to lead to allergic or auto-immune responses. Disadvantages: Poor immunogenicity. Unstable in cells.
NeuVax is a peptide vaccine aimed at preventing or delaying the recurrence of breast cancer in cancer survivors who achieve remission after standard of care treatment (e.g., surgery, radiation, chemotherapy). [1] The product's developer is the US biotechnology company Galena Biopharma.
Gp100:209-217(210M) is a synthetic peptide cancer vaccine consisting of amino acid residues 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen, with a methionine substitution at position 210. [1] It is often referred to as the gp100 cancer vaccine which can also include other peptides based on gp100 (for example gp100:280-288(288V ...
Rindopepimut (CDX-110) is an injectable peptide cancer vaccine [1] which targets a mutant protein called EGFRvIII present in about 25% to 30% of glioblastoma cases. [2]The vaccine consists of the EGFRv3-specific peptide (a 13-amino acid mutant vIII epitope [3]) conjugated to the non-specific immunomodulator keyhole limpet hemocyanin (KLH).
To date, MAGE-A3-derived peptides have been used as vaccines in HLA-A1-positive patients with tumor expressing the respective antigen. MAGE-A peptides have also been used in vaccines consisting of peptide-loaded monocyte-derived dendritic cells (DC). Besides peptide vaccines, recombinant full-length MAGE-A3 and NY-ESO-1 proteins are currently ...
The personalized anti-tumor vaccines are made of specific DNA to target mutated cancer genes. The DNA is derived from a patient’s own biopsy of their tumor. Roughly a third of the patients ...
The duo have partnered since 2016 with a focus on cancer, where Merck is a dominant player for therapies, but the Phase 2 results are the first promising for a any cancer vaccine.
A cancer vaccine, or oncovaccine, is a vaccine that either treats existing cancer or prevents development of cancer. [1] Vaccines that treat existing cancer are known as therapeutic cancer vaccines or tumor antigen vaccines. Some of the vaccines are "autologous", being prepared from samples taken from the patient, and are specific to that patient.