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If you can’t sleep, over-the-counter (OTC) sleep aids like diphenhydramine (ZzzQuil, Benadryl), doxylamine (Unisom), and melatonin might help. But there are a few things to know about taking them safely. Avoid mixing OTC sleeping pills with alcohol and other medications that make you drowsy.
Doxylamine (Unisom) and Alcohol. Like diphenhydramine, doxylamine is an antihistamine that can be used for sleep. Alcohol should be avoided when taking doxylamine due to the risk of additive side effects, including impaired judgment, thinking, and motor skills.
Some OTC medications such as diphenhydramine (Benadryl, Nytol QuickCaps, Tylenol PM, Aleve PM) and doxylamine (Unisom, Nytol Maximum Strength) can interact directly with alcohol as they contain sedating antihistamines.
There is 1 alcohol/food/lifestyle interaction with Unisom SleepTabs (doxylamine). Moderate. Doxylamine Food. Moderate Food Interaction. Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment.
Learn about the dangers of mixing sleeping pills with alcohol, the side effects, sleep issues caused by alcohol, and treatment options.
Unisom may interact with medications you're taking, so talk to your doctor first. You should also avoid taking Unisom with alcohol or other sedatives because this can increase the risk for harmful side effects.
Drinking alcohol can increase certain side effects of doxylamine. Avoid becoming overheated or dehydrated during exercise and in hot weather. Unisom can decrease sweating and you may be more prone to heat stroke.
No, it's best to avoid drinking alcohol while taking doxylamine (Unisom SleepTabs) because doing so raises your risk for severe sleepiness and dizziness. If you drink alcohol regularly and have a hard time stopping completely, talk with your provider what's a safer amount to drink.
Unisom Food, Alcohol, Supplements and Drug Interactions. UNISOM (Brand for SLEEP AID) QTY 30 • 25 MG • Tablet • Near 77381. Add to Medicine Chest. Set Price Alert. More Ways to Save. DOXYLAMINE (dox IL a meen) treats occasional insomnia. It helps you go to sleep. It belongs to a group of medications called antihistamines. Pricing. Drug Information.
Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medication.