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Atrophic non-union results in re-absorption and rounding of bone ends [6] due to inadequate blood supply and excessive mobility of the bone ends. [4] Mal-union: healing occurs but the healed bone has 'angular deformity, translation, or rotational alignment that requires surgical correction'. This is most common in long bones such as the femur. [10]
Typically, wounds that do not heal within three months are classified as chronic. [1] Chronic wounds may remain in the inflammatory phase due to factors like infection or bacterial burden, ischaemia, presence of necrotic tissue, improper moisture balance of wound site, or underlying diseases such as diabetes mellitus. [2] [3] [4]
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
The end goal of wound management is closure of the wound which can be achieved by primary closure, delayed primary closure, or healing by secondary intention, each of which is discussed below. Pain control is a mainstay of wound management, as wound evaluation, wound cleansing, and dressing changes can be a painful process.
Knee injury doctors have long thought that a torn ACL required surgery to fix. New research suggests a non-surgical treatment may be as effective. Torn ACLs may heal with therapy instead of ...
For instance, in wound healing, P21 has been found to allow mammals to heal spontaneously. It even allows some mammals (like mice) to heal wounds without scars. [5] [6] The LIN28 gene also plays a role in wound healing. It is dormant in most mammals. [7] Also, the proteins MG53 and TGF beta 1 play important roles in wound healing. [8]
On the battlefield, some have devised makeshift rituals of cleansing and forgiveness. At the end of a brutal 12-month combat tour in Iraq, one battalion chaplain gathered the troops and handed out slips of paper. He asked the soldiers to jot down everything they were sorry for, ashamed of, angry about or regretted.
"Happiness is a warm puppy:" A variety of famous quotes about dogs from such luminaries as Charles M. Schulz, Mark Twain, Harry S. Truman, and John Steinbeck. The post Best Dog Quotes: 50 Famous ...