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The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. The targeted therapy revolution has arrived, but many of the principles and limitations of chemotherapy discovered by the early researchers still apply.
1977 – US FDA approves tamoxifen for metastatic breast cancer only, not widely popular as chemotherapy remains first line of treatment [27] [28] 1981 – American Dr. Bernard Fisher proves lumpectomy is as effective as mastectomy for breast cancer [4] 1989 – US FDA approves Carboplatin, a derivative of cisplatin, for chemotherapy [10]
Chemotherapy (often abbreviated ... Mustard gas was used as a chemical warfare agent during World War I and was discovered to be a potent suppressor of hematopoiesis ...
DeVita Jr, Vincent T., and Edward Chu. "A history of cancer chemotherapy." Cancer research 68.21 (2008): 8643-8653. Online. Faguet, Guy B. "A brief history of cancer: age‐old milestones underlying our current knowledge database." International journal of cancer 136.9 (2015): 2022-2036. online, down to 1942. Hajdu, Steven I.
In addition to chemotherapy, Thurston also plans to undergo a mastectomy. “Not sure on the order yet,” she explained. “My fertility will be impacted by chemo. I have an appointment with my ...
Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. [3] By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer. [3]
A doctor ordered an MRI and eventually discovered why Doucette experienced such pain — she had a sarcoma, a soft tissue tumor in her elbow. ... “The standard medical therapy is chemotherapy ...
From there, she took a break from chemo, continuing a HER2+-specific regimen until the drugs seemed to "stop working." ... It was then discovered that her pathology had been misread from the start.