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Megestrol acetate is the lead drug of this class for the management of cachexia, and medroxyprogesterone acetate is also used. [ 43 ] [ 44 ] The mechanism of action of the appetite-related effects of these two medications is unknown and may not be related to their progestogenic activity.
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.
A uterotonic, also known as an oxytocic or ecbolic, is a type of medication used to induce contraction or greater tonicity of the uterus. Uterotonics are used both to induce labor and to reduce postpartum hemorrhage. [1] Labor induction in the third trimester of pregnancy may be
Birthing classes, also termed antenatal classes, help the parents to prepare for the baby's birth and care of the newborn. Individual fears and concerns can be discussed with professionals and others in the class. Classes include learning about the process of labor and birth and various medications and other pain management options.
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
Lenalidomide is closely related to thalidomide, which is known to cause severe birth defects, so its use during pregnancy is very likely to harm the fetus. [8] Lenalidomide belongs to a class of drugs known as immunomodulatory imide drugs (IMiDs) or Cereblon E3 ligase modulators, which includes thalidomide and its analogs. [9]
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The drug’s other active metabolite is phenylethylmalonamide (PEMA). Primidone was approved for medical use in the United States in 1954. [7] It is available as a generic medication. [8] In 2020, it was the 269th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [11] [12]
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