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2. Prucalopride - Wikipedia

   en.wikipedia.org/wiki/Prucalopride

   Prucalopride has been given orally to ~2700 patients with chronic constipation in controlled clinical trials. The most frequently reported side effects are headache and gastrointestinal symptoms (abdominal pain, nausea or diarrhea). Such reactions occur predominantly at the start of therapy and usually disappear within a few days with continued ...

3. Functional constipation - Wikipedia

   en.wikipedia.org/wiki/Functional_constipation

   Functional constipation, also known as chronic idiopathic constipation (CIC), is defined by less than three bowel movements per week, hard stools, severe straining, the sensation of anorectal blockage, the feeling of incomplete evacuation, and the need for manual maneuvers during feces, without organic abnormalities.

4. Constipation - Wikipedia

   en.wikipedia.org/wiki/Constipation

   Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. [2] The stool is often hard and dry. [4] Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. [3] Complications from constipation may include hemorrhoids, anal fissure or fecal impaction. [4]

5. The Best Supplements for Men Over 50, According to ... - AOL

   www.aol.com/lifestyle/best-supplements-men-over...

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6. Solitary rectal ulcer syndrome - Wikipedia

   en.wikipedia.org/wiki/Solitary_rectal_ulcer_syndrome

   The most common signs and symptoms are bleeding, which can vary from minor to severe, rectal prolapse and incomplete evacuation (35%-76% of cases). [4] According to one report, constipation is present in about 55% of cases, but diarrhea is present in 20%–40% of cases. [1] Reported symptoms are:

7. Laxative - Wikipedia

   en.wikipedia.org/wiki/Laxative

   Bulk-forming laxatives, also known as roughage, are substances, such as fiber in food and hydrophilic agents in over-the-counter drugs, that add bulk and water to stools so they can pass more easily through the intestines (lower part of the digestive tract). [2] Properties. Site of action: small and large intestines; Onset of action: 12–72 hours

8. Naloxegol - Wikipedia

   en.wikipedia.org/wiki/Naloxegol

   Naloxegol (INN; PEGylated naloxol; [4] trade names Movantik and Moventig) is a peripherally acting μ-opioid receptor antagonist developed by AstraZeneca, licensed from Nektar Therapeutics, for the treatment of opioid-induced constipation. [5] It was approved in 2014 in adult patients with chronic, non-cancer pain. [6]

9. Suppository - Wikipedia

   en.wikipedia.org/wiki/Suppository

   Rectal suppositories are intended for localized or systemic action to relieve pain, constipation, irritation, inflammation, nausea and vomiting, fever, migraines, allergies, and sedation. [ 7 ] [ 8 ] If they cause inflammation, chronic use of suppositories may cause rectal stricture , [ 9 ] but overall this is a safe method of drug delivery.