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  2. Pregabalin - Wikipedia

    en.wikipedia.org/wiki/Pregabalin

    [26] [11] However, food has been found to substantially delay the absorption of pregabalin and to significantly reduce peak levels without affecting the bioavailability of the drug; T max values for pregabalin of 0.6 hours in a fasted state and 3.2 hours in a fed state (5-fold difference), and the C max is reduced by 25–31% in a fed versus ...

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  4. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    However, food has been found to substantially delay the absorption of pregabalin and to significantly reduce peak levels without affecting the bioavailability of the drug; T max values for pregabalin of 0.6 hours in a fasted state and 3.2 hours in a fed state (5-fold difference), and the C max is reduced by 25–31% in a fed versus fasted state ...

  5. Mirogabalin - Wikipedia

    en.wikipedia.org/wiki/Mirogabalin

    As a gabapentinoid, mirogabalin binds to the α 2 δ subunit of voltage-gated calcium channel (1 and 2), but with significantly higher potency than pregabalin. It has shown promising results in Phase II clinical trials for the treatment of diabetic peripheral neuropathic pain .

  6. Funny Dog ‘Checks to Make Sure Mom’s Gone’ Before ... - AOL

    www.aol.com/funny-dog-checks-sure-mom-170000019.html

    Big sister literally checked to make sure mom was really gone then checked out the camera before she started working on freeing the pup! This cracked me up!

  7. File:Pregabalin.svg - Wikipedia

    en.wikipedia.org/wiki/File:Pregabalin.svg

    The following other wikis use this file: Usage on ar.wikipedia.org بريغابالين; Usage on bn.wikipedia.org প্রিগাবালিন

  8. Missing Oregon hiker found dead: Husband arrested, charged ...

    www.aol.com/missing-oregon-hiker-found-dead...

    An investigation into the death of a hiker reported missing in Oregon, who was later found by authorities, has resulted in an arrest in connection to the case.

  9. Cerebellar ataxia, neuropathy, vestibular areflexia syndrome

    en.wikipedia.org/wiki/Cerebellar_ataxia...

    Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is an autosomal recessive late-onset heredodegenerative multisystem neurological disease. The symptoms include poor balance and difficulty walking. Chronic cough and difficulty swallowing may also be present.

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