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Lehninger was born in Bridgeport, Connecticut, US. He earned his BA in English from Wesleyan University (1939) and went on to earn both his MA (1940) and PhD (1942) at the University of Wisconsin–Madison. His doctoral research involved the metabolism of acetoacetate and fatty acid oxidation by liver cells. [1] [4]
Levinthal's paradox is a thought experiment in the field of computational protein structure prediction; protein folding seeks a stable energy configuration. An algorithmic search through all possible conformations to identify the minimum energy configuration (the native state) would take an immense duration; however in reality protein folding happens very quickly, even in the case of the most ...
Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. [1] A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, and metabolism. Over the last decades of the 20th century, biochemistry has become successful at ...
The principle that biological macromolecules catalyze a thermodynamically unfavorable reaction if and only if a thermodynamically favorable reaction occurs simultaneously, underlies all known forms of life. The transfer of electrons from a donor molecule to an acceptor molecule can be spatially separated into a series of intermediate redox ...
The succinate dehydrogenase complex showing several cofactors, including flavin, iron–sulfur centers, and heme.. A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's role as a catalyst (a catalyst is a substance that increases the rate of a chemical reaction).
Bioenergetics is a field in biochemistry and cell biology that concerns energy flow through living systems. [1] This is an active area of biological research that includes the study of the transformation of energy in living organisms and the study of thousands of different cellular processes such as cellular respiration and the many other metabolic and enzymatic processes that lead to ...
Lehninger Principles of Biochemistry, Fourth Edition - David L. Nelson, Michael M. Cox; Biochemistry 5th ed - Jeremy M. Berg, John L. Tymoczko, Lubert Stryer; Biochemistry- Garrett.and.Grisham.2nd.ed; Biochemistry, 2/e by Reiginald and Charles Grisham; Biochemistry for dummies by John T Moore, EdD and Richard Langley, PhD; Stryer L (2007).
Fundamentals of Biochemistry: Life at the Molecular Level is a biochemistry textbook written by Donald Voet, Judith G. Voet and Charlotte W. Pratt. [1] [2] Published by John Wiley & Sons, it is a common undergraduate biochemistry textbook. As of 2016, the book has been published in 5 editions. [3]
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