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Maropitant undergoes 1st-pass metabolism by liver enzymes, mainly CYP2D15 (which has high affinity for maropitant and clears over 90% of it) but also by the lower-affinity CYP3A12. [ 11 ] [ 12 ] Repeat dosing of maropitant eventually saturates CYP2D15, causing the drug to accumulate due to reduced clearance. [ 5 ]
Frunevetmab, sold under the brand name Solensia, is a monoclonal antibody used to treat pain associated with osteoarthritis in cats. [3] It is the first monoclonal antibody drug approved by the US Food and Drug Administration for animal use. [3] Frunevetmab is the international nonproprietary name. [5]
Feline hepatic lipidosis, also known as feline fatty liver syndrome, is one of the most common forms of liver disease of cats. [1] The disease officially has no known cause, though obesity is known to increase the risk. [2] The disease begins when the cat stops eating from a loss of appetite, forcing the liver to convert body fat into usable ...
Over-the-counter (OTC) medicines at FamilyDoctor.org, maintained by the American Academy of Family Physicians. Contains extensive information on over-the-counter drugs and their responsible use, including specific guidance on several drug classes in question-and-answer format and information on common drug interactions.
The quick fix: If you have a gas problem, take an over-the-counter anti-gas drug like Mylanta Gas. Beano, Wolfe says, is another good product, especially if veggies aren't friendly to your system.
Racecadotril, also known as acetorphan, is an antidiarrheal medication which acts as a peripheral enkephalinase inhibitor. [3] Unlike other opioid medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect — it reduces the secretion of water and electrolytes into the intestine. [3]
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