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The function of some dermal bone is conserved throughout vertebrates, although there is variation in shape and in the number of bones in the skull roof and postcranial structures. In bony fish, dermal bone is found in the fin rays and scales. A special example of dermal bone is the clavicle. Some of the dermal bone functions regard ...
Osteochondroma is the most common benign tumor of bone. [1] [2] The tumors take the form of cartilage-capped bony projections or outgrowth on the surface of bones ().[3] [4] It is characterized as a type of overgrowth that can occur in any bone where cartilage forms bone.
Indirect fracture healing, the most common type of bone repair, [10] relies heavily on endochondral ossification. In this type of healing, endochondral ossification occurs within the fracture gap and external to the periosteum. In contrast, intramembranous ossification takes place directly beneath the periosteum, adjacent to the broken bone’s ...
Endochondral ossification is the process by which most vertebrate axial skeletons form into hardened bones from cartilage. This process begins with a cartilage anlage where chondrocyte cells will congregate and start their maturation process. Once the chondrocytes have fully matured at the desired rate, the cartilage tissue will harden into ...
The knee is a modified hinge joint, a type of synovial joint, which is composed of three functional compartments: the patellofemoral articulation, consisting of the patella, or "kneecap", and the patellar groove on the front of the femur through which it slides; and the medial and lateral tibiofemoral articulations linking the femur, or thigh bone, with the tibia, the main bone of the lower ...
A 19-year-old student's persistent knee pain, initially dismissed as a minor ache, turned out to be a rare and aggressive form of bone cancer, necessitating a life-saving leg amputation.. Alicia ...
Symptoms that patients may experience when bone disorders form can include bone deformities, hip pain, overgrowing of bone in an individual's skull which can result in headaches and a loss of hearing, pain and numbness in arm or legs if the spine is affected and an overall weakness in the body particularly in the hip and knee joints. [5]
Runx2 is another important genetic component of Chondroblast formation. It has been found that expressing this gene will result in the suppression of the differentiation of chondroblasts. Expression of this gene will also prompt already formed cartilage to undergo endochondral ossification which will prompt the cartilage to form bone. [citation ...