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Benzoic acid is cheap and readily available, so the laboratory synthesis of benzoic acid is mainly practiced for its pedagogical value. It is a common undergraduate preparation. Benzoic acid can be purified by recrystallization from water because of its high solubility in hot water and poor solubility in cold water. The avoidance of organic ...
The International Programme on Chemical Safety found no adverse effects in humans at doses of 647–825 mg/kg of body weight per day. [ 25 ] [ 26 ] Cats have a significantly lower tolerance against benzoic acid and its salts than rats and mice.
Hippuric acid has long been used as an indicator of toluene exposure; [14] however, there appears to be some doubt about its validity. [15] There is significant endogenous hippuric acid production by humans; which shows inter- and intra-individual variation influenced by factors such as diet, medical treatment, alcohol consumption, etc. [15] This suggests that hippuric acid may be an ...
Across a sample of 23 nicotine salts available for public purchase, the three most common acids used in the formation of nicotine salts were lactic acid, benzoic acid and levulinic acid. [8] Benzoic acid is the most used acid to create a nicotine salt. [9] Nicotine pyruvate is another form of nicotine salt. [10] A chemical reaction with a ...
Benzyl alcohol is subsequently metabolized to benzoic acid. The conjugates of benzoic acid ( hippuric acid and the glucuronide of benzoic acid) are rapidly eliminated in urine. [ 1 ] When given in large doses to laboratory animals, benzyl benzoate can cause hyperexcitation, loss of coordination, ataxia , convulsions , and respiratory paralysis .
Potassium benzoate (E212), the potassium salt of benzoic acid, is a food preservative that inhibits the growth of mold, yeast and some bacteria.It works best in low-pH products, below 4.5, where it exists as benzoic acid.
It can have a slight burning effect that goes away after a few minutes. It is named after Arthur Whitfield (1868–1947), a British dermatologist. [1] The original ointment contains 3% salicylic acid and 6% benzoic acid in a suitable base, such as lanolin or petrolatum. [2] [3] Alternatively, a short-chain alcohol or fatty alcohol can be used ...
UV visible spectrum of protocatechuic acid. Protocatechuic acid (PCA) is a dihydroxybenzoic acid, a type of phenolic acid. It is a major metabolite of antioxidant polyphenols found in green tea. It has mixed effects on normal and cancer cells in in vitro and in vivo studies. [4] It is produced commercially from vanillin. [5]
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