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Benzoic acid is cheap and readily available, so the laboratory synthesis of benzoic acid is mainly practiced for its pedagogical value. It is a common undergraduate preparation. Benzoic acid can be purified by recrystallization from water because of its high solubility in hot water and poor solubility in cold water. The avoidance of organic ...
Hippuric acid is also known as benzoylglycine and is produced from benzoic acid in two steps: first benzoic acid is converted to benzoyl-CoA by the enzyme benzoyl-CoA synthase; then benzoyl-CoA is converted to hippuric acid by benzoyl-CoA:glycine N-acyltransferase. [7] Hippuric acid is the primary urinary metabolite of toluene. [4]
Although the maximum rate of biotransformation of benzoic acid to hippuric acid varied between 17.2 and 28.8 mg.kg-1.h-1 among the six individuals, the mean value (23.0 mg.kg-1.h-1) was fairly close to that provided by daily maximum dose (0.5 g.kg-1.day-1) recommended in the treatment of hyperammonaemia in patients with inborn errors of ureagenesis
The major cause of benzene in soft drinks is the decarboxylation of benzoic acid in the presence of ascorbic acid (vitamin C, E300) or erythorbic acid (a diastereomer of ascorbic acid, E315). Benzoic acid is often added to drinks as a preservative in the form of its salts sodium benzoate (E211), potassium benzoate (E 212), or calcium benzoate ...
Benzyl alcohol is subsequently metabolized to benzoic acid. The conjugates of benzoic acid ( hippuric acid and the glucuronide of benzoic acid) are rapidly eliminated in urine. [ 1 ] When given in large doses to laboratory animals, benzyl benzoate can cause hyperexcitation, loss of coordination, ataxia , convulsions , and respiratory paralysis .
Potassium benzoate (E212), the potassium salt of benzoic acid, is a food preservative that inhibits the growth of mold, yeast and some bacteria.It works best in low-pH products, below 4.5, where it exists as benzoic acid.
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Across a sample of 23 nicotine salts available for public purchase, the three most common acids used in the formation of nicotine salts were lactic acid, benzoic acid and levulinic acid. [8] Benzoic acid is the most used acid to create a nicotine salt. [9] Nicotine pyruvate is another form of nicotine salt. [10] A chemical reaction with a ...