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Corticosteroid-induced lipodystrophy (CIL) is a condition of abnormal fat deposition caused by corticosteroid medications. [1] Fat accumulates in the facial area ("moon face"), dorsocervical region ("buffalo hump"), and abdominal area ("pot belly" or "beer belly"), whereas the thickness of subcutaneous fat in the limbs is decreased. [1]
The medications included prednisone, and methylprednisolone, plus albuterol, beclomethasone, dexamethasone, cromolyn, salmeterol and clarithromycin. Within days of beginning the glucocorticoid treatment, however, the patient began to show symptoms that included major depression, irritability, muscle weakness, and hallucinations ("stars" or ...
Moon face is often associated with Cushing's syndrome [5] [6] or steroid treatment (especially corticosteroids), which has led to it being known as Cushingoid facies. [7]Moon face is a type of corticosteroid-induced lipodystrophy along with "buffalo hump", which in one study occurred in 47% of the 820 patients.
3. Get Enough Sleep. As mentioned, not getting enough sleep can make weight loss harder. To help, aim for at least seven hours a night. To improve your sleep and hit that number, try:. Waking up ...
Adults can also lose anywhere from 3 to 8 percent of muscle mass per decade after their 20s—and less muscle means fewer calories burned at rest, which can lead to weight gain over time, he ...
Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
Cardiac physiologist Jane Graham, from York, said she hoped to access a weight-loss jab through the NHS to lose two stone (12.7kg). The 60-year-old had a heart attack nine years ago, and alongside ...
higher potency corticosteroids, more frequent application, extended duration of treatment, [3] use of occlusion, infancy/childhood, location [2] Diagnostic method: Visual inspection of skin for visible signs of skin atrophy [1] Prevention: Intermittent maintenance therapy; increasing duration of interval between applications [4] Management