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The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
With regard to morphology, the initial lesion that characterizes a condition is known as the "primary lesion", and identification of such a lesions is the most important aspect of the cutaneous examination. [30] Over time, these primary lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions". [1]
Primary cutaneous CD-30 positive T-cell lymphoproliferative disorders are a family of skin-localized extranodal lymphoid neoplasms that develop from mature postthymic T cells. Currently used classification schemes identify primary cutaneous anaplastic large cell lymphoma and lymphomatoid papulosis (LyP).
Skin cancer is the most common form of cancer nationwide each year, the Centers for Disease Control and Prevention (CDC) says, as about 6.1 million adults are treated for basal cell and squamous ...
A study examining over 4,000 biopsied skin lesions identified clinically as seborrheic keratoses showed 3.1% were malignancies. Two-thirds of those were squamous cell carcinoma. [11] To date, the gold standard in the diagnosis of seborrheic keratosis is represented by the histolopathologic analysis of a skin biopsy. [12]
[14] [30] The vast majority of cSCC cases are located on exposed skin, and are often the result of ultraviolet exposure. cSCC usually occurs on portions of the body commonly exposed to the sun; the face, ears, neck, hands, or arms. The primary sign is a growing bump that may have a rough, scaly surface, and flat, reddish patches.
Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1] Over time affected skin may become darker, stiffen, peel, or bleed. [1] [3] There are two main types of pellagra, primary and secondary. [1]
Turner said she never had any lesions or moles on her skin — which happens in about 3% of melanoma cases — and that doctors have given her a "50/50 chance" to survive