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When the bone marrow no longer produces normal red blood cells, hematocrit levels deviate from normal as well and thus can possibly be used in detecting acute myeloid leukemia. [37] It can also be related to other conditions, such as malnutrition, water intoxication, anemia, and bleeding.
Mean corpuscular volume (MCV) is the average volume of a red blood cell and is calculated by dividing the hematocrit (Hct) by the concentration of red blood cell count. [citation needed] = [] Normal range: 80–100 fL (femtoliter)
An anemia is normocytic when the red blood cells (RBCs) are of normal size. RBCs are normocytic when the mean corpuscular volume (MCV) is between 80 and 100 femtolitres (fL), which is within the normal and expected range. However, the hematocrit and hemoglobin are decreased. [1]
Anemia (also spelled anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen.This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function.
The large volume percentage of red blood cells at a normal hematocrit level leaves little room for cell motion and deformation without interacting with a neighboring cell. Calculations have shown that the maximum volume percentage of red blood cells without deformation is 58% which is in the range of normally occurring levels. [10]
In patients with anemia, it is the MCV measurement that allows classification as either a microcytic anemia (MCV below normal range), normocytic anemia (MCV within normal range) or macrocytic anemia (MCV above normal range). Normocytic anemia is usually deemed so because the bone marrow has not yet responded with a change in cell volume.
A vitamin B12 level of less than 200 pg/mL is considered deficient. Treatment First, have your health care provider run blood tests to see if you truly have a B12 deficiency.
This calculation is to correct for the severity of the anemia. A value of 45% (or 0,45 L/L) is usually used as a normal hematocrit for males. [4] 2.The next step is to correct for the longer life span of prematurely released reticulocytes in the blood—a phenomenon of increased red blood cell production. This relies on a table: