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The dermatome is the dorsal portion of the paraxial mesoderm somite which gives rise to the skin . In the human embryo, it arises in the third week of embryogenesis . [ 2 ] It is formed when a dermomyotome (the remaining part of the somite left when the sclerotome migrates), splits to form the dermatome and the myotome. [ 2 ]
[4] [5] However, the segmentation clock model is highly evolutionarily conserved. [ 6 ] Intrinsic expression of "clock genes" must oscillate with a periodicity equal to the time necessary for one somite to form, for example 30 minutes in zebrafish, 90 minutes in chicks, and 100 minutes in snakes.
A dermatome is an area of skin that is mainly supplied by afferent nerve fibres from the dorsal root of any given spinal nerve. [ 1 ] [ 2 ] There are 8 cervical nerves (C1 being an exception with no dermatome), 12 thoracic nerves , 5 lumbar nerves and 5 sacral nerves .
The notochord and the neural tube activate the protein SHH, which helps the somite to form its sclerotome. The cells of the sclerotome express the protein PAX1 that induces the cartilage and bone formation. The neural tube activates the protein WNT1 that expresses PAX 2 so the somite creates the myotome and dermatome.
Paraxial mesoderm, also known as presomitic or somitic mesoderm, is the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. ...
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English: Dermatomes and major cutaneous nerves in a ventral view. Español: Dermatomas y nervios cutáneos en una vista ventral. Date: 17 October 2010: Source: File ...
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