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Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
[3] [5] All age groups can be affected from sleep disorders after TBI, including children [1] and adolescents. [ 6 ] There are several risk factors that are associated with occurring sleep disorders, such as lower years of education, severity of head injury and occurrence of residuals symptoms, for example headache or dizziness.
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
This condition was first discovered in 1995 by Melberg et al. when they described 5 members of a 4-generation Swedish family where cerebellar ataxia and sensorineural deafness presented as an autosomal dominant trait, 4 of them had narcolepsy and 2 had diabetes mellitus. The oldest members had psychiatric symptoms, neurological anomalies, and ...
Cataplexy without narcolepsy is rare and the cause is unknown. The term cataplexy originates from the Greek κατά ( kata , meaning "down"), and πλῆξις ( plēxis , meaning "strike") [ 4 ] and it was first used around 1880 in German physiology literature to describe the phenomenon of tonic immobility also known as " playing possum " (in ...
Cardiologists Say It Can Cause Stroke. Currie Engel. November 11, 2024 at 6:30 AM. Why Doctors Are Saying 'No' To Neck Manipulation Danielle Daly.
Brain injury can occur at the site of impact, but can also be at the opposite side of the skull due to a contrecoup effect (the impact to the head can cause the brain to move within the skull, causing the brain to impact the interior of the skull opposite the head-impact). While impact on the brain at the same site of injury to the skull is the ...
Unfortunately, the term 'mini-stroke' is misleading. The #1 Mini-Stroke Symptom Most People Miss, According to a Cleveland Clinic Neurologist Skip to main content
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